Acetaminophen (Tylenol) Dosage Calculator
Calculate safe acetaminophen doses for adults and children. Adult max is 3,000-4,000 mg/day (lower with liver disease). Pediatric dose is 10-15 mg/kg every 4-6 hours, max 75 mg/kg/day or 5 doses in 24 hours.
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Calculate acetaminophen/Tylenol dosing for infants, children, and adults.
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Why: Calculate acetaminophen/Tylenol dosing for infants, children, and adults.
How: Enter your values in the calculator fields below, keep units consistent, then run the calculation to see results and any step-by-step work shown on this page.
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Overdose Warning: Acetaminophen overdose can cause severe liver damage. Do not exceed recommended doses. Seek immediate medical attention if overdose is suspected.
For informational purposes only — not medical advice. Consult a healthcare professional before acting on results.
Acetaminophen (Tylenol) is one of the most commonly used analgesic and antipyretic medications worldwide. Pediatric dose is 10-15 mg/kg every 4-6 hours (max 75 mg/kg/day). Adult dose is 325-1000 mg per dose, max 3000-4000 mg/day. Always use weight-based dosing for children.
Sources: FDA, AAP, WHO, Lexicomp.
Key Takeaways
- • Weight-based dosing is more accurate than age-based for children
- • Check ALL medications for hidden acetaminophen (600+ products)
- • Reduce dose with liver disease or heavy alcohol use
- • Never exceed 4000 mg/day (3000 mg for chronic use)
Did You Know?
How Does Acetaminophen Work?
Mechanism
Inhibits COX enzymes in the CNS, reducing prostaglandin synthesis. Minimal anti-inflammatory effect; gentler on stomach than NSAIDs.
Metabolism
Primarily liver via glucuronidation/sulfation. Small portion forms toxic NAPQI; glutathione neutralizes it. Overdose depletes glutathione.
Formulations
Infant drops 80 mg/mL; children's liquid 160 mg/5 mL; tablets 325-650 mg. Use weight-based dosing and convert to formulation volume.
Expert Tips
Formulations Comparison
| Product | Strength | Typical Use |
|---|---|---|
| Infant Drops | 80 mg/mL | 0-2 years |
| Children's Liquid | 160 mg/5mL | 2-11 years |
| Chewable | 160 mg/tablet | 2-11 years |
| Regular Strength | 325 mg/tablet | 12+ years |
| Extra Strength | 500 mg/tablet | Adults |
Frequently Asked Questions
What is the safe acetaminophen dose for children?
Pediatric dose is 10-15 mg/kg every 4-6 hours, max 75 mg/kg/day or 5 doses in 24 hours. Always use weight-based dosing, not age charts, for accuracy.
What is the maximum daily acetaminophen dose for adults?
Adult max is 3,000-4,000 mg/day. Reduce to 2,000 mg/day with liver disease or chronic heavy alcohol use (3+ drinks/day).
Can I alternate acetaminophen and ibuprofen for fever?
Yes, alternating every 3-4 hours is sometimes used for persistent fever. Keep careful records to avoid dosing errors. Never exceed max daily dose of either medication.
Is acetaminophen safe during pregnancy?
Acetaminophen is generally considered the safest OTC pain reliever during pregnancy when used at recommended doses. NSAIDs should be avoided, especially in the third trimester.
What medications contain hidden acetaminophen?
Over 600 medications contain acetaminophen including Percocet, Vicodin, NyQuil, DayQuil, Excedrin, and Tylenol PM. Always check all medications to prevent accidental overdose.
When should I seek medical attention for acetaminophen overdose?
Seek immediate help if overdose is suspected. Initial symptoms may be mild (nausea); liver damage may not appear for 24-72 hours. Call Poison Control: 1-800-222-1222.
Key Statistics
Official Data Sources
⚠️ Disclaimer: This calculator is for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider or pharmacist before administering medications. Acetaminophen overdose can cause severe liver damage.
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